diff --git a/test-suites/full-stack-compose/runtime/requirements.txt b/test-suites/full-stack-compose/runtime/requirements.txt
index 0e51957f8..b6258ffb8 100644
--- a/test-suites/full-stack-compose/runtime/requirements.txt
+++ b/test-suites/full-stack-compose/runtime/requirements.txt
@@ -2,7 +2,7 @@
 # SPDX-License-Identifier: Apache-2.0
 
 # Keep the runtime subset synchronized with dstack/vmm/requirements.txt.
-cryptography==48.0.1
+cryptography==50.0.0
 eth-hash[pycryptodome]==0.7.1
 eth-keys==0.7.0
 eth-utils==5.3.0